All results
26 results
-
A Multicenter, Interventional, Retrospective and Prospective study of Enzyme Replacement Therapy (VPRIV) Clinical Outcomes and Safety in Gaucher Disease Type 1 Patients Previously Treated with Substrate Reduction Therapy
Adult patients with Gaucher Disease Type 1 who have previously received SRT (substrate replacement therapy) and are now receiving ERT (enzyme replacement…
- Ages
- N/A
- Sexes
- All
-
A Multicenter, Randomized, Double-blind, Placebo-controlled, Phase 2 Study to Investigate the Efficacy and Safety of Asapiprant in Hospitalized Adults With COVID-19
Individuals diagnosed with COVID-19 are being asked to take part in a research study of an investigational drug called Asapiprant (BGE 175). This drug is being…
- Ages
- N/A
- Sexes
- All
-
A Natural History and Outcome Measure Discovery Study of PRPF31 Mutation–Associated Retinal Dystrophy (20226317)
A Natural History and Outcome Measure Discovery Study of PRPF31 Mutation–Associated Retinitis Pigmentosa Patients with Retinitis Pigmentosa with PRPF31 Gene…
- Ages
- N/A
- Sexes
- All
-
A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Dose Range Finding Clinical Trial to Evaluate the Tolerability, Safety, and Efficacy of PRAX-944 in the Treatment of Adults with Essential Tremor
This multi-center, randomized, double-blind, placebo-controlled, dose-range-finding clinical trial will assess the efficacy, safety, and tolerability of…
- Ages
- N/A
- Sexes
- All
-
A Phase 3, Multi-Center, Double-Blind, Randomized, Placebo-Controlled Trial To Evaluate The Efficacy And Safety Of Reldesemtiv in Patients With Amyotrophic Lateral Sclerosis (ALS)
This is a Phase 3, double-blind, randomized, placebo-controlled trial of Reldesemtiv in patients aged 18 to 80 with ALS. A drug named "Reldesemtiv" is being…
- Ages
- N/A
- Sexes
- All
-
A Phase 3, multi-centre long-term extension study to assess the safety and efficacy of GSK3196165 in the treatment of rheumatoid arthritis.
This research study is being done to learn more about how well an investigational study drug, called otilimab, works and how safe it is when taken for a longer…
- Ages
- N/A
- Sexes
- All
-
A Randomized Clinical Trial Evaluating Fenofibrate for Prevention of Diabetic Retinopathy Worsening (Protocol AF)
This randomized trial will evaluate the effect of fenofibrate compared with placebo for prevention of diabetic retinopathy (DR) worsening or center-involved…
- Ages
- N/A
- Sexes
- All
-
A Randomized, Double-blind, Placebo-controlled, Phase 2a Multiple Ascending Dose Study to Examine the Safety, Tolerability and Efficacy of AV 001 in Participants Hospitalized with Confirmed Severe COVID-19 Disease (20211987)
The purpose of this research study is to assess the safety, tolerability (primary objective), efficacy, and target engagement (secondary objective) of multiple…
- Ages
- N/A
- Sexes
- All
-
A Two-Stage, Double-Blind, Placebo-Controlled Phase 2 Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of OP-101 (dendrimer n-acetyl-cysteine) in Patients with Severe COVID-19
Ashvattha Therapeutics, Inc. has begun a clinical study of an investigational drug (also known as the "study drug") called OP-101 as a possible treatment for…
- Ages
- N/A
- Sexes
- All
-
A randomized, double blind, parallel-group, placebo controlled study to evaluate the efficacy and safety of IBP-9414 in premature infants 500-1500g birth weight in the prevention of necrotizing enterocolitis – The Connection study (20191002)
Your child was born, or is expected to be born, prematurely. Premature infants can get a serious inflammatory condition, called necrotizing enterocolitis…
- Ages
- N/A
- Sexes
- All