Liver Cancer

Hepatocellular carcinoma accounts for most liver cancers and occurs more often in men than women. It is usually diagnosed in people age 50 or older.

Hepatocellular carcinoma is not the same as metastatic liver cancer, which starts in another organ, such as the breast or colon, and spreads to the liver.

In most cases, the cause of liver cancer is long-term damage and scarring of the liver, called cirrhosis. Cirrhosis may be caused by:

  • Alcohol abuse
  • Autoimmune diseases of the liver
  • Hepatitis B or hepatitis C virus infection
  • Iron overload in the body
  • Long-term inflammation of the liver

People with hepatitis B or C are at high risk of liver cancer, even if they do not develop cirrhosis. Some people who have a high chance of developing liver cancer may get regular blood tests and ultrasounds to see whether tumors are developing.

A biopsy of the tumor must be done to accurately diagnose hepatocellular carcinoma. Treatment options depend on how advanced the cancer is. Radiation and chemotherapy are options, as well as surgery. In addition, targeted therapy and immunotherapy through medication may be used.

Contact Us

Call 904-633-0797 to make an appointment.


  • Maged P. Ghali, M.D.
    Chief, Division of Gastroenterology; Program Director, Gastroenterology Fellowship
    Specializes in Gastroenterology


  1. UF Health Gastroenterology – Emerson

    Building 1, Suite 300
    4555 Emerson St.
    Jacksonville, FL 32207

  2. UF Health Gastroenterology – Jacksonville

    Tower I, 5th Floor
    580 West 8th Street
    Jacksonville, FL 32209

  3. UF Health Gastroenterology – North

    Suite 3100
    15255 Max Leggett Parkway
    Jacksonville, FL 32218