MAIN MENU
QUICK LINKS
CONNECT WITH US

Button
Coronavirus (COVID-19) updates, visitor restrictions and resources →
Now offering telemedicine through our Virtual Visit online program for primary care and specialty care visits → Virtual Visit appointments are available for new and existing UF Health patients. Check the FAQ section and Request an Appointment section below for more information.

Call (904) 383-1052 to make an appointment or call your physician’s office if you have questions specific to your health needs.

Eosinophilic fasciitis

  • Definition
    • Eosinophilic fasciitis is a syndrome in which muscle tissue under the skin, called fascia, becomes swollen, inflamed and thick. The hands, arms, legs, and feet can swell quickly. The condition is very rare.

      The disease may look similar to scleroderma but is not related.

  • Causes
    • The cause of eosinophilic fasciitis is unknown. In people with this condition, white blood cells called eosinophils, build up in the muscles and tissues. Eosinophils are linked to allergic reactions. The syndrome is more common in people ages 30 to 60.

  • Symptoms
    • Symptoms may include:

  • Exams and Tests
    • Tests that may be done include:

  • Treatment
    • Corticosteroids and other immune-suppressing medicines are used to relieve symptoms. These medicines are more effective when started early in the disease. Nonsteroidal anti-inflammatory drugs (NSAIDs) may also help reduce symptoms.

  • Outlook (Prognosis)
    • In most cases, the condition goes away within 3 to 5 years. However, symptoms may last longer or come back.

  • Possible Complications
    • Arthritis is a rare complication of eosinophilic fasciitis. Some people may develop very serious blood disorders or blood-related cancers, such as aplastic anemia or leukemia. The outlook is much worse if blood diseases occur.

  • When to Contact a Medical Professional
    • Call your health care provider if you have symptoms of this disorder.

  • Prevention
    • There is no known prevention.

  • References
    • Lee LA, Werth VP. The Skin and Rhematic Diseases. In: Firestein GS, Budd RC, Gabriel SE, et al, eds. Kelley's Textbook of Rheumatology. 9th ed. Philadelphia, PA: Elsevier Saunders; 2012:chap 43.