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Culture-negative endocarditis

  • Definition
    • Culture-negative endocarditis is an infection and inflammation of the lining of one or more heart valves, but no endocarditis-causing germs can be found on a blood culture. This is because certain germs do not grow well in a laboratory setting, or some people have received antibiotics in the past that keep such germs from growing.

      Endocarditis is usually a result of a blood infection. Bacteria can enter the bloodstream during certain medical procedures, including dental procedures. Then bacteria can travel to the heart, where they can settle on damaged heart valves.

  • Alternative Names
    • Endocarditis (culture-negative)

  • References
    • Baddour LM, Freeman WK, Suri RM, Wilson WR. Cardiovascular infections. In: Mann DL, Zipes DP, Libby P, Bonow RO, Braunwald E, eds. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 10th ed. Philadelphia, PA: Elsevier Saunders; 2014:chap 64.