Optic neuritis

  • Definition
    • The optic nerve carries images of what the eye sees to the brain. When this nerve become swollen or inflamed, it is called optic neuritis. It may cause sudden, reduced vision in the affected eye.

  • Alternative Names
    • Retro-bulbar neuritis; Multiple sclerosis - optic neuritis; Optic nerve - optic neuritis

  • Causes
  • Symptoms
    • Symptoms may include:

      • Loss of vision in 1 eye over an hour or a few hours
      • Changes in the way the pupil reacts to bright light
      • Loss of color vision
      • Pain when you move the eye
  • Exams and Tests
    • A complete medical exam can help rule out related diseases. Tests may include:

  • Treatment
    • Vision often returns to normal within 2 to 3 weeks with no treatment.

      Corticosteroids given through a vein (IV) or taken by mouth (oral) may speed up recovery. However, the final vision is no better with steroids than without. Oral steroids may actually increase the chance of recurrence.

      Further tests may be needed to find the cause of the neuritis. The condition causing the problem can then be treated.

  • Outlook (Prognosis)
    • People who have optic neuritis without a disease such as multiple sclerosis have a good chance of recovery.

      Optic neuritis caused by multiple sclerosis or other autoimmune diseases has a poorer outlook. However, vision in the affected eye may still return to normal.

  • Possible Complications
    • Complications may include:

      • Body-wide side effects from corticosteroids
      • Vision loss

      Some people who have an episode of optic neuritis will develop nerve problems in other places in the body or develop multiple sclerosis.

  • When to Contact a Medical Professional
    • Call your health care provider right away if you have a sudden loss of vision in one eye, especially if you have eye pain.

      If you have been diagnosed with optic neuritis, call your health care provider if:

      • Your vision decreases.
      • The pain in the eye gets worse.
      • Your symptoms do not improve within 2 to 3 weeks.
  • References
    • Eze P, Sra SK, Sra KK, Friedlaender M, Trocme SD. Immunology of neurologic and endocrine diseases that affect the eye. In: Tasman W, Jaeger EA, eds. Duane's Foundations of Clinical Ophthalmology. 2013 ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2013:vol 2,chap 35.

      Jacobs DA, Guercio JR, Balcer LJ. Inflammatory optic neuropathies and neuroretinitis. In: Yanoff M, Duker JS, eds. Ophthalmology. 4th ed. Philadelphia, PA: Elsevier; 2014:chap 9.7.

      Prasad S, Balcer LJ. Abnormalities of the optic nerve and retina. In: Daroff RB, Jankovic J, Mazziotta JC, Pomeroy SL, eds. Bradley's Neurology in Clinical Practice. 7th ed. Philadelphia, PA: Elsevier; 2016:chap 17.

      Purvin V, Glaser JS. Topical diagnosis: prechiasmal visual pathways. In: Tasman W, Jaeger EA, eds. Duane's Ophthalmology. 2013 ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2013:vol 2,chap 5.