Hypervitaminosis D

  • Definition
    • Hypervitaminosis D is a condition that occurs after taking very high doses of vitamin D.

  • Alternative Names
    • Vitamin D toxicity

  • Causes
    • The cause is excess intake of vitamin D. The doses need to be very high, far above what most medical providers normally prescribe.

      There has been a lot of confusion about vitamin D supplementation. It is extremely unusual for anybody to need more than 2,000 IU of vitamin D a day.

      For most people, vitamin D toxicity only occurs with Vitamin D doses above 10,000 IU per day.

  • Symptoms
  • Exams and Tests
  • Treatment
    • Your provider will likely tell you to stop taking vitamin D. In severe cases, other treatment may be needed.

  • Outlook (Prognosis)
    • Recovery is expected, but permanent kidney damage can occur.

  • Possible Complications
    • Health problems that can result from taking too much vitamin D over a long time include:

      • Dehydration
      • Hypercalcemia
      • Kidney damage
      • Kidney stones
  • When to Contact a Medical Professional
    • Call your health care provider if:

      • You or your child shows symptoms of hypervitaminosis D and has been taking more vitamin D than the recommended daily allowance
      • You or your child shows symptoms and has been taking a prescription or over-the-counter form of vitamin D
  • Prevention
    • To prevent this condition, pay careful attention to the correct vitamin D dose.

  • References
    • Greenbaum LA. Rickets and hypervitaminosis D. In: Kliegman RM, Stanton BF, St. Geme JW III, Schor NF, eds. Nelson Textbook of Pediatrics. 20th ed. Philadelphia, PA: Elsevier; 2015:chap 51.

      Gropper SS, Smith JL. Fat-soluble vitamins. In: Gropper SS, Smith JL, eds. Advanced Nutrition and Human Metabolism. 6th ed Independence, KY: Wadsworth Publishing; 2012:chap 10.