Neurology: Clinical Research

University of Florida neurologists serve as primary investigators in Phase II-IV clinical research studies that will someday determine the most accurate outcomes available in neurological disease treatment. Many of these clinical research trials are granted to just a few specialists and hospitals throughout the nation or the world.

A patient who meets guidelines outlined in a study protocol can participate in a clinical trial. Neuroscience physicians and their research teams provide participating patients with details of the study and regularly monitor and record their progress.

For more information about patient participation in the Neuroscience Institute Clinical Research Program, call 904-244-9856.

The UF Department of Neurology at UF Health Jacksonville is enrolled in the following research trials:

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Clinical Trial Details

Title
Safety and Therapeutic Measures of Transcranial Cathodal Direct Current Stimulation (tDCS) in Patients with Refractory Focal Epilepsy
Study Description

The purpose of this research is to learn more about Transcranial Cathodal Direct Current Stimulation (tDCS) and to see if it can help reduce the frequency of seizures in both adults and children with refractory focal epilepsy (epilepsy that cannot be well controlled by anti-seizure medication).

The use of tDCS is investigational in this study, which means that it is not approved by the FDA for the treatment of refractory focal epilepsy. Prior research suggests that daily tDCS may reduce the frequency of seizures in some patients with refractory focal epilepsy, although in some cases an increase in seizure frequency has also been observed. These changes may be due to tDCS decreasing the over-reaction of the region of your brain that your doctor believes causes your seizures.

There are a total of 14 visits, some of which may be conducted remotely. We expect that your involvement in this research will last approximately 6 months.


After you sign a consent document and agree to participate in this study, the following evaluations will be done:

1. A review of your medical history and medications. This includes a review of your seizure history and treatment.
2. We will ask you for a copy of a recent EEG and MRI. If your MRI is not suitable for the study, the study doctor may ask you to have another MRI.
3. A urine pregnancy test if you are female and able to have children.
4. A physical and neurological exam. 

You will be financially compensated to cover travel and hotel expenses.

The study staff is available via phone and email to answer questions if you are interested in participating in the trial or would like to learn more about the study.

Open Enrollment
Contact Name: Layla Jamil
Contact Phone: (904) 244-9686
Contact Email: layla.jamil@jax.ufl.edu
Investigators

Principal Investigator
Katherine A. Zarroli, M.D.
Neurology

Sub Investigator
Ramon E. Bautista, M.D., M.B.A.
Neurology

Sub Investigator
Suparna R. Krishnaiengar, M.B.B.S. (M.D.)
Neurology