MAIN MENU
QUICK LINKS
CONNECT WITH US

Button
Coronavirus (COVID-19) updates, visitor restrictions and resources →
Now offering telemedicine through our Virtual Visit online program for primary care and specialty care visits → Virtual Visit appointments are available for new and existing UF Health patients. Check the FAQ section and Request an Appointment section below for more information.

Call (904) 383-1052 to make an appointment or call your physician’s office if you have questions specific to your health needs.

Clinical Trial Details

Title
Impact of the PCSK9 Inhibitor Evolocumab on the Pharmacodynamic Effects of Clopidogrel in Patients with Atherosclerotic Cardiovascular Disease and High On-Treatment Platelet Reactivity
Study Description

To investigate the effects of evolocumab in addition to statin therapy on HPR rates and platelet reactivity in patients with atherosclerotic cardiovascular disease (ASCVD) and HPR while on clopidogrel treatment. Secondary aims will include the effects on cholesterol levels.

Patients will be randomly assigned to receive either evolocumab 420 mg s.c. or placebo (0.9% sodium chloride s.c. injection).

Open Enrollment
Contact Name: Hope Dover
Contact Phone: (904) 244-2682
Contact Email: jennifer.dover@jax.ufl.edu
Investigators

Principal Investigator
Dominick J. Angiolillo, M.D., Ph.D., FACC
Medicine

Sub Investigator
Francesco Franchi, M.B.Ch.B. (M.D.)
Medicine

Sub Investigator
Fabiana Rollini, M.B.Ch.B. (M.D.)
Medicine