All results
11 results
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A Phase 2, Double-Blind, Randomized, Parallel-Group, Placebo-Controlled, Multi-Center Study to Evaluate the Efficacy, Safety, and Tolerability of Oral Omadacycline in Adult Subjects with Nontuberculous Mycobacterial (NTM) Pulmonary Disease Caused by
This study is investigating the efficacy, safety, and tolerability, of an antibiotic medication called omadacycline in adult subjects with Nontuberculous…
- Ages
- 18 Years - 100 Years
- Sexes
- All
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A Phase 2/3, Randomized, Double-blind, Placebo-controlled, Multicenter, Prospective Study to Assess the Efficacy, Safety, and Pharmacokinetics of Orally Administered Epetraborole in Patients with Treatment-refractory Mycobacterium avium Complex Lung
The purpose of this study is to learn about the effects of epetraborole in patients with refractory MAC, including to assess the efficacy for treating…
- Ages
- 18 Years - 100 Years
- Sexes
- All
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A Phase III, Multicentre, Randomised, Double-blind, Chronic-dosing, Parallel-group, Placebo-controlled Study to Evaluate the Efficacy and Safety of Two Dose Regimens of Tozorakimab in Participants with Symptomatic Chronic Obstructive Pulmonary Disease
The purpose of this Phase III study is to evaluate the efficacy and safety of tozorakimab, a human immunoglobulin G1 monoclonal antibody (mAb). Tozorakimab is…
- Ages
- 18 Years - 100 Years
- Sexes
- All
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A Randomized, Double-blind, Placebo-controlled, Phase 2a Multiple Ascending Dose Study to Examine the Safety, Tolerability and Efficacy of AV-001 Injection in Patients Hospitalized with Pneumonia Due To COVID-19 or Other Respiratory Infections
A Phase 2a, randomized, double-blind, placebo-controlled, multiple ascending dose study in patients who are hospitalized with presumed pneumonia requiring…
- Ages
- 18 Years - 100 Years
- Sexes
- All
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A randomised, double-blind, placebo-controlled, parallel group, dose-finding study evaluating efficacy, safety and tolerability of BI 1291583 qd over at least 24 weeks in patients with bronchiectasis (Airleaf™)
A study to test whether different doses of BI 1291583 help people with bronchiectasis. If you join this study, you may receive the study drug being tested, BI…
- Ages
- 18 Years - 100 Years
- Sexes
- All
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CROSS: Cholesterol Rule out For Sepsis Study
This research study will help us to determine if initial cholesterol levels can aid in establishing a diagnosis of sepsis. 2.2.a. Inclusion criteria. To enroll…
- Ages
- 18 Years - 100 Years
- Sexes
- All
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ENCORE - A Randomized, Double-Blind, Placebo-Controlled, Active Comparator, Multicenter Study to Evaluate the Efficacy and Safety of an Amikacin Liposome Inhalation Suspension (ALIS)-Based Regimen in Adult Subjects with Newly Diagnosed Nontuberculous
The purpose of this study is to evaluate the effect and safety of amikacin liposome inhalation suspension (ALIS) study treatment on patient-reported symptoms…
- Ages
- 18 Years - 100 Years
- Sexes
- All
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Exclusion criteria: 1. Cystic fibrosis or bronchopulmonary dysplasia 2. In law enforcement custody or wards of the state (i.e., DCF custody) 3. Known pregnancy 4. Critically ill (ESI triage level 1) 5. Intubated , on BiPAP, on CPAP, bag valve mask
This study will analyze gene expression and other laboratory data from biological samples collected from participants with suspected respiratory, urinary,…
- Ages
- 18 Years - 100 Years
- Sexes
- All
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HEAD injury Serum markers and Multi-modalities for Assessing Response to Trauma (HeadSMART II)
The purpose of this research study is to develop and validate tests in order to aid in the diagnosis and prognosis of mild Traumatic Brain Injury…
- Ages
- 18 Years - 100 Years
- Sexes
- All
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Telehealth Program to Reduce Sepsis Readmissions
The objective of this study is to evaluate the feasibility of a telehealth program for post-sepsis care. Patients (18 years old) Being treated for sepsis SOFA…
- Ages
- 18 Years - 100 Years
- Sexes
- All