Pathology and Laboratory Medicine: Molecular Pathology
The addition of molecular technologies to standard pathological methods results
in a better understanding of disease diagnosis. Molecular technologies are used
to monitor infectious disease and cancer treatment, as well as determine disease
severity by better characterizing pathogenicity.
Molecular technologies have further evolved and now play important roles in drug
development and drug prescribing. Molecular technology is the key to the expanding
role of healthcare screening and detection in preventing disease.
The molecular diagnostic facility is now expanding its testing capabilities. In
addition to molecular diagnostic tests, faculty members perform research in the
field of cancer biomarker studies. The molecular laboratory has been named a Roche
Molecular Center of Excellence, the 25th center across the nation to become part
of this prestigious network.
Prognostic Testing of Breast Cancer
- Her2, Estrogen Receptor, Progesterone Receptor, Ki-67, P53
- Her2: Breast cancer (FISH)
- MSI: Colon and endometrial carcinoma
- KRAS: Colon and lung cancer
- BRAF: Colon cancer (MSI-H and advanced stage colon cancer); Papillary thyroid carcinoma;
- EFGR: Non-small cell lung cancer
- JAK2: Chronic myeloproliferative neoplasm
- HFE: Hemochromatosis
- Factor II and V: Inherited genetic disorder for hypercoagulation
- HPV/pap test