Pulmonary nocardiosis

  • Definition
    • Pulmonary nocardiosis is an infection of the lung with the bacteria, Nocardia asteroides.

  • Alternative Names
    • Nocardiosis - pulmonary

  • Causes
    • Nocardia infection develops when you breathe in (inhale) the bacteria. The infection causes pneumonia-like symptoms. The infection can spread to any part of the body.

      People at highest risk for nocardia infection are those with a weakened immune system. This includes people who have:

      • Been taking steroids or other medicines that weaken the immune system for a long time
      • Cushing disease
      • An organ transplant
      • HIV
      • Lymphoma

      Other people at risk include those with chronic lung problems related to smoking, emphysema, or other infections such as tuberculosis.

  • Symptoms
    • Entire body:

      • Fever (comes and goes)
      • General ill feeling (malaise)
      • Night sweats

      Gastrointestinal system:

      Lungs and airways:

      • Breathing difficulty
      • Chest pain not due to heart problems
      • Coughing up blood
      • Cough with mucus
      • Rapid breathing
      • Shortness of breath

      Muscles and joints:

      Nervous system:

      • Change in mental state
      • Confusion
      • Dizziness
      • Headache
      • Seizures


  • Exams and Tests
    • Your doctor or nurse will examine you and listen to your lungs using a stethoscope. You may have abnormal lung sounds, called crackles. Tests that may be done include:

  • Treatment
    • The goal of treatment is to control the infection. Antibiotics are used, but it may take a while to get better. You must keep taking the medications for at least 3 months.

      Surgery may be needed to remove or drain infected areas.

      Your health care provider may tell you to stop taking any medicines that weaken your immune system. Never stop taking any medicine before talking to your health provider first.

  • Outlook (Prognosis)
    • The outcome is often good when the condition is diagnosed and treated quickly.

      The outcome is poor when the infection spreads outside the lung, treatment is delayed, or the person has a serious disease that leads to or requires long-term suppression of the immune system.

  • Possible Complications
  • When to Contact a Medical Professional
    • Call your health care provider if you have symptoms of this disorder. Early diagnosis and treatment may improve the chance of a good outcome.

  • Prevention
    • Be careful when using corticosteroids. Use these drugs sparingly, in the lowest effective doses and for the shortest periods of time possible.

      Some patients with an impaired immune system may need to take antibiotics for long periods of time to prevent the infection from returning.

  • References
    • Limper AH. Overview of pneumonia. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine. 24th ed. Philadelphia, PA: Elsevier Saunders; 2011:chap 97.

      Torres A. Pyogenic bacterial pneumonia and lung abscess. In: Mason RJ, Broaddus CV, Martin TR, et al. Murray & Nadel's Textbook of Respiratory Medicine. 5th ed. Philadelphia, PA: Elsevier Saunders; 2010:chap 32.