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Meningitis

  • Definition
    • Meningitis is an infection of the membranes covering the brain and spinal cord. This covering is called the meninges.

  • Causes
    • The most common causes of meningitis are viral infections. These infections usually get better without treatment. But, bacterial meningitis infections are very serious. They may result in death or brain damage, even if treated.

      Meningitis may also be caused by:

      • Chemical irritation
      • Drug allergies
      • Fungi
      • Parasites
      • Tumors

      Many types of viruses can cause meningitis:

      • Enteroviruses: These are viruses that also can cause intestinal illness.
      • Herpes viruses: These are the same viruses that can cause cold sores and genital herpes. However, people with cold sores or genital herpes do not have a higher chance of developing herpes meningitis.
      • Mumps and HIV viruses can cause aseptic meningitis.
      • West Nile virus: This virus is spread by mosquito bites and has become a cause of viral meningitis in most of the United States.
  • Symptoms
    • Viral meningitis occurs more often than bacterial meningitis, and is milder. It usually occurs in the late summer and early fall. It most often affects children and adults under age 30.

      Bacterial meningitis is an emergency. You will need immediate treatment in a hospital. Symptoms usually come on quickly, and may include:

      • Fever and chills, especially in newborns and children
      • Mental status changes
      • Nausea and vomiting
      • Sensitivity to light (photophobia)
      • Severe headache
      • Stiff neck (meningismus)

      Other symptoms that can occur with this disease:

      You cannot tell if you have bacterial or viral meningitis by how you feel. Your health care provider must find out the cause. Go to the hospital emergency department right away if you think you have symptoms of meningitis.

  • Exams and Tests
    • Your provider will examine you. This may show:

      • Fast heart rate
      • Fever
      • Mental status changes
      • Stiff neck

      If the provider thinks you have meningitis, a lumbar puncture (spinal tap) should be done to remove a sample of spinal fluid (cerebrospinal fluid, or CSF) for testing.

      Other tests that may be done include:

  • Treatment
    • Antibiotics are used to treat bacterial meningitis. Antibiotics do not treat viral meningitis. But antiviral medicine may be given to those with herpes meningitis.

      Other treatments will include:

      • Fluids through a vein (IV)
      • Medicines to treat symptoms, such as brain swelling, shock, and seizures
  • Outlook (Prognosis)
    • Early diagnosis and treatment of bacterial meningitis is essential to prevent permanent neurological damage. Viral meningitis is usually not serious, and symptoms should disappear within 2 weeks with no lasting complications.

  • Possible Complications
  • When to Contact a Medical Professional
    • If you think that you or your child has symptoms of meningitis, get emergency medical help immediately. Early treatment is key to a good outcome.

  • Prevention
    • Certain vaccines can help prevent some types of bacterial meningitis:

      • Haemophilus vaccine (HiB vaccine) given to children helps
      • Pneumococcal vaccine is given to children and adults
      • Meningococcal vaccines is given to children and adults; some communities hold vaccination campaigns after an outbreak of meningococcal meningitis.

      Household members and others in close contact with people who have meningococcal meningitis should receive antibiotics to prevent becoming infected.

  • References
    • Swartz MN, Nath A. Meningitis: bacterial, viral, and other. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine. 24th ed. Philadelphia, PA: Elsevier Saunders; 2012:chap 420.

      Tunkel AR, Van de Beek D, Scheld WM. Acute meningitis. In: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 8th ed. Philadelphia, PA: Elsevier Churchill Livingstone; 2015:chap 89.