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Macroglossia

  • Definition
    • Macroglossia is a disorder in which the tongue is larger than normal.

  • Information
    • Macroglossia is usually caused by an increase in the amount of tissue on the tongue, rather than by a growth, such as a tumor.

      This condition can be seen in certain inherited or congenital (existing at birth) disorders, including:

      • Acromegaly (buildup of too much growth hormone in the body)
      • Beckwith-Wiedemann syndrome (growth disorder that causes large body size, large organs, and other symptoms)
      • Congenital hypothyroidism (decreased production of thyroid hormone)
      • Diabetes (high blood sugar caused by body producing too little or no insulin)
      • Down syndrome (extra copy of chromosome 21, which causes problems with physical and intellectual functioning)
      • Lymphangioma or hemangioma (malformations in the lymph system or buildup of blood vessels in the skin or internal organs)
      • Mucopolysaccharidoses (a group of diseases that cause large amounts of sugar to build up in the body's cells and tissues)
      • Primary amyloidosis (a buildup of abnormal proteins in the body's tissues and organs)
  • References
    • Dorland's Online Medical Dictionary. Available at: dorlands.com/def.jsp?id=100062359. Accessed May 15, 2015.

      Stedman's Online Medical Dictionary. Available at: www.stedmansonline.com/content.aspx?id=mlrM0100001416&termtype=t. Accessed May 15, 2015.